News archive

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Overcoming multidrug resistance with P-glycoprotein-inhibiting polymeric therapeutics

The Journal of Controlled Release has published a study on overcoming multidrug resistance in solid tumors using polymeric nanotherapeutics developed at IMC in collaboration with scientists from the Institute of Microbiology and Motol University Hospital.

Ostatní

Wetting of surface grafted hydrophilic-b-hydrophobic block copolymer brushes

Researchers systematically revealed how bottom and top block thicknesses govern wetting in amphiphilic polymer brushes, thereby unlocking switchable hydrophilic-hydrophobic surfaces.

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Biobased hydrogels for use in smart agrochemicals

We prepared poly (itaconic acid) / nanoclay hydrogels with prolonged release of the dye showing their potential application in agrochemical delivery systems.

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Effects of copolymer on the interfacial tension in polymer blends

The Macromolecular Theory and Simulation journal published the invited review article on theories of polymer blends compatibilizations by copolymer addition.

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Comparison of various UHMWPE formulations in contemporary total joint replacements

We have demonstrated that the highly crosslinked UHMWPE formulations with biocompatible stabilizers exhibit the highest resistance to long-term oxidative degradation.

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The influence of bio-based monomers on structure and thermal properties of polyurethanes

In this study, we successfully prepared fully bio-based polyurethane elastomers exhibiting comparable properties to conventional petrochemical polyurethanes.

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Elena Tomšík awarded the Werner von Siemens Prize for research in energy storage

The award reflects an outstanding contribution to the research of conductive polymers and their application in energy storage in supercapacitors.

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Dendrimer-modified Pebax membranes for enhanced CO₂ separation

Scientists from IMC studied the impact of dendrimers on selectivity and permeability of Pebax membranes for CO₂/N₂ separation. The results were published in Polymer journal.

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Smart sensor for early detection of inflammation around implants

Scientists from IMC developed a polymer sensor for early detection of implant-related inflammation by measuring changes in free calcium levels in the tissue microenvironment.

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Dr. Jiří Kotek elected as a member of the Academy Council

On Tuesday, March 18, 2025, Dr. Jiří Kotek, Director of the Institute of Macromolecular Chemistry of the CAS, was elected by the Academy Assembly as a member of the Academy Council for the term 2025–2029.

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Synthesis of fluorinated polymer brushes as coatings for medical applications

The "grafting-from" polymerization of
*N*-(2-fluoroethyl) acrylamide provides fluorinated surfaces with antifouling properties.

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Swelling mechanism of polyoxazoline-based gel polymer electrolytes

Researchers from IMC elucidated the mechanism of swelling of lithium solutions in polyoxazoline networks, and its effect on the applicability of the obtained gel polymer electrolytes in Lithium-ion batteries.

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Tailoring polyester-based diblock copolymers for boron-enhanced drug delivery

Newly synthesized and well-characterized polyester-based diblock copolymers self-assemble into nanoparticles suitable for delivery of boron-containing anticancer drugs.

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Advances in the synthesis of multifunctional polymethacrylamides

An IMC team discovered that poly(2-isopropenyl-2-oxazoline) can be cleanly modified with thiols in water, affording a wide range of useful functional polymethacrylamides with numerous applications.

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Upconversion nanoparticles for hypericin delivery and multimodal imaging

IMC scientists published in Nanoscale new system for diagnostics and photodynamic therapy of tumors based on upconversion nanoparticles and hypericin.

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Lithium phthalocyanine (γ-structure) as a molecular oxygen sensor

Our new methodology ensures accurate lithium-phthalocyanine radical synthesis in the γ-crystalline phase, directly applicable as a precise and reliable oxygen sensor.

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Conductive films cast from highly stable PEDOT and PEDOT/silver colloids

Researchers from IMC developed highly stable PEDOT and PEDOT/silver aqueous colloids which are able to form conductive films.

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Cationic-hydrophilic di-block copolymers: Surface-shielded vectors for gene delivery

For gene delivery, INC scientists have developed di-block cationic copolymers that form DNA-loaded particles with residual charge shielding.

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Neuron 2024 award for connecting science and business in the hands of IMC scientists

This prestigious award highlights the collaboration between researchers from the Biomedical Polymers Department and the commercial sector and establishment of the startup Sophomer, s.r.o., which develops diagnostic tests utilizing the synthetic molecule Sophomer™ F10.

Ostatní

Detailed characterization of pH-responsive polymer nanoparticles for drug delivery

The European Polymer Journal published a physicochemical study dedicated to the release of stable nitroxide radicals from polymer transport systems.