News archive

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Award for Dr. Petr Štěpánek

Dr. Petr Štěpánek was awarded the Jaroslav Heyrovský Honorary Medal for Merit in Chemical Sciences by the President of the CAS.

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Design of new magnetic polymers by means of theoretical modeling

We proposed a model designed for optimization of the chemical structure - magnetic properties relationship of novel polymers for spintronic applications.

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Polymeric eco-packaging with antimicrobial and antioxidant activity

In collaboration with Polish colleagues, have developed polymeric biodegradable active packaging materials that extend the shelf-life of fruits and protect consumers against pathogenic bacteria.

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Bio-responsive polymer probes for reactive oxygen species detection via MRI

Scientists from IMC and IKEM developed bio-responsive polymer probes to detect pathologies related to the overproduction of reactive oxygen species using magnetic resonance imaging.

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Preparation of polyamino acid microgels and determination of nanomechanical properties in the swollen state

We developed the soft polyamino acid microgels and further the procedure to determine and define their nanomechanical properties in the hydrated state using the AFM method.

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Temoporfin-conjugated PEGylated upconversion colloid for photodynamic therapy of cancer

Upconverting nanoparticles coated with temoporphyrin-containing polymer after irradiation with near-infrared light completely cured experimental animals suffering from tumors using photodynamic therapy.

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Star copolymers as structurally tunable macromolecular carriers for peptide vaccine delivery

Researchers from IMC and Barinthus Biotherapeutics reveal advancements in structurally tunable polymer carriers for peptide vaccine delivery, enhancing immune system activationin vivo.

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Microfluidic controlled self-assembly of polylactide (PLA)-based linear and graft copolymers into nanoparticles with diverse morphologies

IMC researchers demonstrated microfluidic-controlled self-assembly of PLA-based copolymers into nanoparticles, using advanced characterization techniques.

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Surface functionalization with well-defined and low-fouling PiPOx brushes

The publication in the Polymer Chemistry journal describes the development of PIPOx layers that provide high fouling resistance and offer broad surface functionalization possibilities.

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Polypyrrole/tungsten carbide composites for energy storage

The scientists from IMC discovered that the addition of tungsten carbide nanoparticles and safranin to the polymerization media of pyrrole has produced composites with improved electrical conductivity and gravimetric capacitance.

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Postmodification with polycations enhances properties of alginate microcapsules used for cell encapsulation

Within an international collaboration, IMC participated at the research focused on improving properties of alginate microcapsules used for pancreatic cells encapsulation within a new (type 1) diabetes therapy.

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New approach to synthesis of polymeric architectures with ultra-high chain density

An IMC team developed a new method of synthesis of complex polymeric architectures, unlocking access to severalfold higher polymer chain density than possible with current approaches.

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Superior Antitumor Efficacy of pH-Responsive Vesicles, So-Called 'Polymersomes

Researchers from IMC elucidated the relationship between the structure, properties, and antitumor activity of polymersomes, demonstrating that pH-responsive polymersomes exhibit excellent therapeutic efficacy in animal models.

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Polypyrrole/tannic acid aerogels as efficient adsorbents of Cr(VI) ions

The addition of tannic acid to the polymerization medium of polypyrrole with nanofibrillated cellulose has significantly enhanced the adsorption capacity of Cr(VI) ions up to 549.5 mg g⁻¹.

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Polymer surfaces with antimicrobial properties due to hexagonal domains of silver nanoparticles

High-resolution scanning electron microscope installed at IMC enabled us to visualize hexagonal domains of silver nanoparticles on the surface of PEEK polymer. The silver particle domains were created in the UCT laboratories in order to impart antimicrobial properties to the polymer surface.

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Polymer-bound fluorescent probes for imaging of tumor-associated proteases

We developed protease-activated fluorescent probes for image-guided surgery in which a fluorophore/quencher pair was bound to hydrophilic biocompatible copolymer.

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Solvent effects on surface-grafted and free poly[N-(2-hydroxypropyl)methacrylamide] chains during surface-initiated RAFT polymerization

Solvent proticity and/or polarity influences the solution propagation rate, leading to mass transfer limitations and a concomitant discrepancy in the molar masses of poly[N-(2-hydroxypropyl)methacrylamide] chains formed in solution and grafted from the surface during surface-initiated RAFT polymerization.

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Polymer-based antibody mimetics (iBodies) as immune checkpoint blocker

Scientists from IMC, together with colleagues at IOCB, have developed polymeric anti-human PD-L1 antibody mimetics (iBodies) that specifically target human hPD-L1 and block the PD-1/PD-L1 interaction in vitro with the same efficacy as monoclonal antibodies.

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The electrostatic interaction of charged macromolecules takes place differently than expected

IMC’s scientists participated in a study demonstrating the influence of ionization changes during the interactions of oppositely charged (bio)macromolecules.

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Polymer composites for eco-friendly remediation of hexavalent chromium ions from wastewater

Scientists from IMC together with colleagues from BUT developed the free-standing bacterial celulose/polypyrrole membrane for the effective adsorption/reduction of the hexavalent chromium ions from polluted water.