News archive

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Neuron 2024 award for connecting science and business in the hands of IMC scientists

This prestigious award highlights the collaboration between researchers from the Biomedical Polymers Department and the commercial sector and establishment of the startup Sophomer, s.r.o., which develops diagnostic tests utilizing the synthetic molecule Sophomer™ F10.

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Cationic-hydrophilic di-block copolymers: Surface-shielded vectors for gene delivery

For gene delivery, INC scientists have developed di-block cationic copolymers that form DNA-loaded particles with residual charge shielding.

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Detailed characterization of pH-responsive polymer nanoparticles for drug delivery

The European Polymer Journal published a physicochemical study dedicated to the release of stable nitroxide radicals from polymer transport systems.

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Ultrathin nanofibrous membranes based on poly(γ-benzyl-L-glutamate)

The study in the Journal of Chemical Physics presents highly porous ultrathin nanofibrous membranes based on synthetic polypeptide prepared by electrospinning aimed at tissue engineering application.

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Enhanced electrochemical performance of polyaniline-boron doped diamond electrode for supercapacitor applications

Synergy between appropriate boron doping nanodiamond support and optimized PANI suspension is studied. The interaction and performance of the composite electrodes depend on the crystal size, electrical resistivity and sp2 carbon content of the support.

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Temperature- and pH-sensitive polymeric nanoparticles for controlled drug release

Particles designed to disintegrate and potentially release drugs in tumor tissue enable reduction of systemic side effects during oncological therapy.

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Stimuli-responsive hybrid polymer nanoparticles intumor therapy

The publication in Expert Opinion on Drug Delivery journal presents a vision of hybrid polymeric nanoparticles responsive to external stimuli as promising agents for antitumor therapy.

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Czech scientists contribute to the development of eco-friendly solar cells

The IMC scientists in collaboration with researchers from Linköping University in Sweden, has achieved significant progress in the development of eco-friendly organic solar cells that offer a greener alternative to conventional silicon based solar panels.

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Breakthrough in diagnosing infections in joint replacements: Czech interdisciplinary team develops smart materials

The development of innovative polymer sensors holds promise for effective detection of postoperative complications.

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Probing the inner structure and dynamics of pH-sensitive block copolymer nanoparticles with nitroxide radicals using scattering and EPR techniques

IMC researchers demonstrated EPR spectroscopy analyzes pH-responsive TEMPO-labeled nanoparticles for controlled drug delivery and molecular-level nanoparticle structural dynamics.

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Smart pH-responsive microparticles for bacteria capture

Innovative microparticles transform into vesicles at acidic pH, trapping bacteria and enabling targeted drug delivery.

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Polymeric nanotherapeutics with acetylsalicylic acid derivatives for the treatment of acute or chronic inflammation

We developed nanosystems with controlled release of acetylsalicylic acid derivatives that reduce the production of pro-inflammatory mediators and inhibit inflammation-promoting cyclooxygenases.

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Design of new magnetic polymers by means of theoretical modeling

We proposed a model designed for optimization of the chemical structure - magnetic properties relationship of novel polymers for spintronic applications.

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Polymeric eco-packaging with antimicrobial and antioxidant activity

In collaboration with Polish colleagues, have developed polymeric biodegradable active packaging materials that extend the shelf-life of fruits and protect consumers against pathogenic bacteria.

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Bio-responsive polymer probes for reactive oxygen species detection via MRI

Scientists from IMC and IKEM developed bio-responsive polymer probes to detect pathologies related to the overproduction of reactive oxygen species using magnetic resonance imaging.

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Preparation of polyamino acid microgels and determination of nanomechanical properties in the swollen state

We developed the soft polyamino acid microgels and further the procedure to determine and define their nanomechanical properties in the hydrated state using the AFM method.

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Temoporfin-conjugated PEGylated upconversion colloid for photodynamic therapy of cancer

Upconverting nanoparticles coated with temoporphyrin-containing polymer after irradiation with near-infrared light completely cured experimental animals suffering from tumors using photodynamic therapy.

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Award for Dr. Petr Štěpánek

Dr. Petr Štěpánek was awarded the Jaroslav Heyrovský Honorary Medal for Merit in Chemical Sciences by the President of the CAS.

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Star copolymers as structurally tunable macromolecular carriers for peptide vaccine delivery

Researchers from IMC and Barinthus Biotherapeutics reveal advancements in structurally tunable polymer carriers for peptide vaccine delivery, enhancing immune system activationin vivo.

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Microfluidic controlled self-assembly of polylactide (PLA)-based linear and graft copolymers into nanoparticles with diverse morphologies

IMC researchers demonstrated microfluidic-controlled self-assembly of PLA-based copolymers into nanoparticles, using advanced characterization techniques.