News archive

Ostatní

Highly effective synthetic polymer-based blockers of non-specific interactions

Researchers from IMC have developed highly effective synthetic polymer blockers of non-specific interactions, which make it possible to replace currently used proteins of animal origin.

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Polymersome nanovaccines enhance antitumor immunity with co‑delivered antigens and adjuvants

IMC and Radboud University Medical Center developed polymersome nanovaccines boosting antitumor immunity by co-delivering antigens and adjuvants to dendritic cells.

Ostatní

Aluminosilicate networks as Lewis acid catalysts: Synthesis and characterization

The journal Inorganic Chemistry has published a comprehensive study that reveals the mechanism of formation of catalytically active aluminosilicate networks and provides a detailed insight into the structure of the resulting Lewis acid centers.

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Cancer cell membrane targeting with tailored highly defined polymers

Scientists from the IMC CAS developed in collaboration with the IOCB CAS highly defined "octopus" peptoid polymers targeting cancer cell membranes.

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Degradation of polyolefins with phenolic stabilizers subjected to ionizing or non-ionizing radiation

IMC researchers showed that phenolic stabilizes (such as vitamin E) exhibit both antioxidant and prooxidant properties, depending on the irradiation type.

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Sustainable aerogels made of poly (itaconic acid) for wastewater remediation

International Journal of Biological Macromolecules recently published the use of aerogels for dyes adsorption. These aerogels are considered a promising adsorbent material for wastewater remediation.

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Non-conventional light-mediated therapy with ferrocene-based polymer micelles

Scientists from the IMC developed non-conventional light-triggered approach to killing cancer cells using ferrocene-containing polymer micelles.

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Tannic acid-modified magnetic nanoparticles reduce oxidative stress in liver

Magnetic iron oxide nanoparticles modified with tannic acid and N-acetylcysteine-chitosan conjugate reduce oxidative stress in liver of prediabetic rats.

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38 nm biodegradable poly[N-(2-hydroxypropyl) methacrylamide] nanogels by dispersion polymerization

The scientists from the IMC developed the conditions of dispersion polymerization for the preparation of 38 nm core shell biodegradable, hydrophilic and reactive nanogels.

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Biobased ultralow-density polyurethane foams with enhanced recyclability

We have prepared ultra-light polyurethane foams from renewable feedstock showing increased recyclability, which contribute to circular economy and solving plastic waste concerns.

Ostatní

Novel natural-based alginate-pectin networks dually crosslinked with Ca2+/Zn2+ ions for the delivery of lipophilic phytotherapeutics

The close collaboration of the IMC CAS, MUNI Pharm and VRI resulted in the design of advanced hybrid alginate-pectin networks, proposed as the long-term site-specific treatment of intestinal inflammation.

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Mechanically strong and extensible monolithic hydrogels with rapid response to temperature change

Strong and tough monolithic non-porous hydrogels have been developed: poly(N-isopropylacrylamide) interlaced with hydroxypropylmethylcellulose. Some exhibited an exceptionally rapid response to temperature changes.

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New highly hydrophilic methacrylamide-based drug carriers for cancer treatment

We have designed, synthesized and tested in vivo efficient water-soluble polymer chemotherapeutics that are able to be accumulated in tumor tissue.

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Polymerization of renewable itaconic acid in deep eutectic monomers

Scientists from IMC in cooperation with Polish colleagues, synthesized polyitaconates from renewable resources as more environmental-friendly alternatives to conventional petrochemical polyacrylates.

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PhD projects – Call for Applications 2024/2025

We are looking for new PhD students who are interested in advanced material and biomedical research.

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Straightforward preparation of hydrogel layers on various substrates by electron beam irradiation

Scientists from the IMC participated in technology biocompatibilization of implant surfaces. The polymer on the implant surface is irradiated and cross-linked by an electron beam.

Ostatní

Biodegradation of aliphatic polyurethane foams in soil

The published study investigated the impact of structural changes in polyurethane foams on the rate of biodegradation in soil and ecotoxicological safety.

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Inhibition of the tumor protein CCL2 improves the efficacy of anticancer therapy with nanomedicines

Scientists from IMC participated in the development of new inhibitors of tumor proteins, whose significantly increase the efficacy of anti-cancer therapy using nanomedicines.

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Soft hydrogels with double porosity for tissue engineering

The journal Macromolecular Bioscience has published a study focusing on characterization of 3D polymeric scaffolds intended for the reparation of soft tissue.

Ostatní

Radiosensitizing molybdenum nanoclusters conjugated with a biocompatible copolymer for radiodynamic therapy

Scientists from the IMC coated octahedral molybdenum nanoclusters by biocompatible copolymer to prepare theranostic tool for photo/radiodynamic applications.