News archive

Researchers from IMC substantially contributed to the characterization of nanoparticles, which exhibit promising therapeutic properties for the treatment of Hungtington disease - a neurodegenerative disease of brain.

Interesting research published in Pharmaceutics manufactured novel amphiphilic, biocompatible and thermo-responsive PLA-b-PTEGMA copolymers synthesized via one-pot controlled RAFT-ROP polymerizations with fine-tuneable LCST. NPs prepared from them encapsulated and release paclitaxel by temperature-triggered drug release mechanism in relevant pathophysiological temperatures.

IMC scientists developed a method using electron beam irradiation to create nonbiofouling hydrogel coatings on implantable materials, improving biocompatibility and in vivo performance. Crosslinkable double bond concentration in the copolymer is crucial for stability and uniformity of the formed hydrogel layer.

We are deeply saddened to announce that on April 7th 2023, the physical chemist and leading expert in polymer chemistry Prof. Ing. Pavel Kratochvíl, DrSc. passed away.

A study was published in Materials, comparing the above characterizations on hydrogen-bond-rich rubbery elasto-plastic nanocomposites containing a monodisperse spherical rigid filler.

The journal Macromolecular Research published a study describing the synthesis and characterization of biocompatible and biodegradable polymers based on poly(L-glutamic acid) bearing zwitterionic groups. The developed materials can be used in tissue engineering.

Cationic amphiphilic animal venoms like melittin can be complexed with polyanionic nanoparticles to form potential therapeutic agents with high efficacy. Article was published in the European Polymer Journal.

The journal Molecules has published a study describing the synthesis and characterization of biocompatible phosphorus-containing polymers that can be used as highly sensitive probes in 31P MRI imaging of internal body structures.

Upconverting NaYF4:Yb,Er nanoparticles modified by bisphosphonate-terminated poly(ethylene glycol) and Rose Bengal produced reactive oxygen species potentially to kill cancer cells.

Between 19 and 21 March 2023, IMC has organized an international conference focused on the presentation of the recent results and sharing of experience in the field of cancer treatment and diagnostics.

A new method for the synthesis of N-methacryloxysuccinimide based polymer brushes via surface-initiated atom-transfer radical polymerization and subsequent post-polymerization modification was presented in the journal Progress in Organic Coatings.

Journal Nanoscale Advances published an article describing an excellent platform for fundamental research on non-aqueous nanofluids, with metal-polymer and metal-metal interactions unperturbed by the presence of solvents or chemical residuals.

An international team of scientists has succeeded in developing a new and universal, temperature-independent system for non-destructive cell harvesting. By biofunctionalization of polymer brushes, surfaces enabling adhesion, cultivation and subsequent on-demand harvesting of fibroblasts were prepared.

Journal Pharmaceutics published an article presenting the design, synthesis, and preliminary biological evaluation of polymer-antibacterial peptide constructs.

Researchers from the IMC synthesized efficient adsorbents for water purification due to their enhanced adsorption performance and the possibility of facilitated separation from solution by a magnetic field.

Scientists, in collaboration with industrial developers, have developed a technology that can prepare a fully synthetic polymer and make it significantly easier and cheaper to carry out analyses aimed at proving the presence of a pathogen or a specific antibody in the body.

An international team of researchers developed pH-responsive giant polymer vesicles.

Scientists from IMC described how 2-hydroxyethyl methacrylate (HEMA) can be polymerized rapidly in a controlled fashion generating high MW poly(HEMA) and providing direct access to amphiphilic copolymers.

Recently published study compares the biodistribution and tumor accumulation of four fluorescently labeled polymer conjugates and low molecular weight fluorescent labels in tumor cells.

Journal of Materials Chemistry B has published a study presenting a new synthetic method for the fabrication of the PANI sensing layer for the potentiometric detection of iron.