Topic details
| Topic | Microparticulate contrast agents transforming excitation signal for biomedical application |
|---|---|
| Supervisor | Michal Babič, Ph.D. |
| Department | Polymer and colloid immunotherapeutics |
| Description | The project is focused on synthesis and characterisation of polymer particles for biomedical application, which can generate a contrast signal via a transformation of excitation pulse. Particles will be synthesised by heterogeneous polymerisation techniques, especially by dispersion and emulsion polymerisation, and by coacervation. Effects of a morphology and matrix composition of hybrid particles on contrast signal parameters will be studied. Effects of a type, amount and a distribution of transforming dye in polymer particles on contrast properties will be studied as well. The main aim of the project is to find conditions of synergy between properties of polymer matrix and converting dye. Testing on animal models will be done in cooperation with 1. Faculty of medicine, Charles University in Prague. " |
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