Conference Venue
Conference Office
E-mail: etrych
Address:
Institute of Macromolecular Chemistry CAS
Heyrovského nám. 2
162 00 Prague 6
Czech Republic
http://www.imc.cas.cz
Institute of Macromolecular Chemistry CAS
Heyrovského nám. 2
162 00 Prague 6
Czech Republic
http://www.imc.cas.cz
Programme
- Programme (PDF for printing) | Book of Abstracts
- Sunday 19. 3. | Monday 20. 3. | Tuesday 21. 3. | Posters
SUNDAY March 19th |
|
| 18:30 – 21:00 | Welcome reception at Institute of Macromolecular Chemistry CAS |
MONDAY March 20th |
|
| 8:50 – 9:00 | Tomáš Etrych, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic
Introduction |
| 1st section: New materials | |
| Chair: Tomáš Etrych | |
| 9:00 – 9:30 | Jonathan A. Coulter, School of Pharmacy, Queen’s University Belfast, BT9 BL, UK Achieving Impact from University Research – A nanotechnology tale |
| 9:30 – 10:00 | Ian Teasdale, Johannes Kepler University, Linz, Austria Phosphorus-based polymers as a tunable, biodegradable platform for polymer therapeutics |
| 10:00 – 10:20 | Libor Kostka, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic
Polymerization platform for synthesis of multi-arm carriers |
| 10:20 – 10:40 | Pavla Bojarová, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Glycopolymers targeting galectins in biomedicine |
| 10:40 – 11:00 | Posters and coffee |
| 2nd section: Cancer metabolism and microenvironment | |
| Chair: Eva Randárová | |
| 11:00 – 11:30 | Karel Smetana, Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague and BIOCEV, Vestec, Czech Republic Role of cancer-associated fibroblasts in cancer microenvironment |
| 11:30 – 12:00 | Alexander Detappe, Institut de Cancérologie Strasbourg Europe, Strasbourg, France Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma |
| 12:00 – 12:20 | Juan Bautista De Sanctis, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic Effect of ASA nanopolymers on tumour antigen expression in human cell lines |
| 12:20 – 12:40 | Marek Kovář, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Linear and star HPMA copolymer conjugates bearing doxorubicin and ritonavir derivate overcomes P-gp and STAT3-mediated tumor chemoresistance |
| 12:40 – 12:50 | Future directions in cancer targets - discussion led by Marek Kovář |
| 12:50 – 14:10 | Lunch |
| 3rd section: Chemotherapy | |
| Chair: Jun Fang | |
| 14:10 – 14:40 | Danuta Radzioch, McGill University Health Centre, Montreal, Canada Magnetically-guided chemotherapy-carrying magneto-aerotactic bacteria induces immune cells infiltration and their activation resulting in inhibition of colorectal cancer growth |
| 14:40 – 15:00 | Yohann Corvis, Université Paris Cité, CNRS, INSERM, UTCBS lab, Paris, France Nanocrystals engineering for anticancer therapies |
| 15:00 – 15:20 | Milada Šírová, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Polymer carrier of cytotoxic drugs with P-gp overcoming capacity in the treament of chemoresistant tumors |
| 15:20 – 15:50 | Marián Hajdúch, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic Academic driven drug development: From molecular targets to proof-of-concept clinical trials |
| 15:50 – 16:20 | Posters and coffee |
| 4th section: Directions beyond cancer | |
| Chair: Nathalie Mignet | |
| 16:20 – 16:40 | Kazumi Yokomizo, Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan Application of polymeric micelle nanocarrier to microbes and infections |
| 16:40 – 17:00 | Makoto Anraku, Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan The preparation and validation of chitosan tablets that rapidly disperse and disintegrate as an oral adsorbent in the treatment of lifestyle-related diseases |
| 17:00 – 17:20 | Eva Randárová, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Polymer-based drug delivery systems for treatment and diagnosis of inflammatory diseases |
| 17:20 – 17:40 | Tomáš Špringer, Institute of Photonics and Electronics of the Czech Academy of Sciences, Prague, Czech Republic pH-triggered drug release from nanocarriers investigated by surface plasmon resonance biosensor |
| Dinner at Břevnov Monastery | |
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TUESDAY March 21st |
|
| 1st section: Theranostics | |
| Chair: Steffen Hackbarth | |
| 9:00 – 9:30 | Carolina de Aguiar Ferreira, Departments of Radiology, Pharmacology & Toxicology and Biomedical Engineering, Michigan State University, USA Exploring Biological Applications of Radionuclides: From Cancer Theranostics to Tumor Immunology |
| 9:30 – 10:00 | Jean-Luc Coll, Team Cancer Targets and Experimental Therapeutics, Univ. Grenoble Alpes, INSERM U1209, CNRS UMR5309, Institute for Advanced Biosciences, Grenoble, France NIR-I and NIR-II optically active nanosystems and their use for theranostic treatment of cancer |
| 10:00 – 10:20 | Kirakci Kaplan, Institute of Inorganic Chemistry of the Czech Academy of Sciences, Husinec–Řež, Czech Republic Octahedral Molybdenum Cluster Complexes for Photodynamic Applications |
| 10:20 – 10:40 | Petr Hermann , Department of Inorganic Chemistry, Faculty of Science, Universita Karlova, Prague, Czech Republic Macrocyclic chelators for metal radioisotopes and influence of phosphorus acid pendant arms. |
| 10:40 – 11:00 | Posters and coffee |
| 2nd section: PDT | |
| Chair: Jean-Luc Coll | |
| 11:00 – 11:30 | Steffen Hackbarth, Photobiophysics, Institute of Physics, Humboldt-Universität zu Berlin, Germany Sometimes less is more – How photosensitization in vivo depends on intensity |
| 11:30 – 12:00 | Jun Fang, Faculty of Pharmaceutical Sciences, Sojo University, Japan Polymeric nano-probes for tumor-targeted photodynamic therapy and imaging |
| 12:00 – 12:20 | Marina Tavares, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic pH-Responsive Polymer Nanomedicines for Tumor-Targeted Photodynamic Therapy and Imaging |
| 12:20 – 12:50 | Kamil Lang, Institute of Inorganic Chemistry of the Czech Academy of Sciences, Husinec–Řež, Czech Republic Molybdenum nanoclusters for X ray-induced photodynamics |
| 12:50 – 14:10 | Lunch |
| 3rd section: Imaging | |
| Chair: Carolina Ferreira | |
| 14:10 – 14:40 | Nathalie Mignet, Université Paris Cité, CNRS, INSERM, UTCBS lab, Paris, France Bioconjugates made of albumin as targeted imaging agent |
| 14:40 – 15:00 | Eliška Grosmanová, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Synthesis of polymer-based multifunctional nanotherapeutics decorated with antimicrobial, cell-penetrating, targeting or therapeutic oligopeptides |
| 15:00 – 15:20 | Martin Kaňa, Department of Otorhinolaryngology and Head and Neck Surgery, 1st Medical Faculty, Charles University and University Hospital Motol, Czech Republic Intraoperative Fluorescence-Guided Surgery of Malignant Head-and-neck Tumors and Metastases |
| 15:20 – 15:40 | Dora Konečná, Institute of Biochemistry and Experimental Oncology 1st Medical Faculty, Charles University and Department of Neurosurgery, Military University Hospital Prague, Czech Republic Protease-activated probes for the visualization of glioblastoma |
| 15:40 – 15:50 | Future directions in imaging and theranostics - discussion led by Carolina de Aguiar Ferreira |
| 15:50 – 16:10 | Closing of the meeting and coffee |
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Presented posters |
|
| Kateřina Běhalová, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Antitumor activity of HPMA polymeric conjugates bearing HIV protease inhibitor derivatives |
|
| Alena Braunová, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Micellar copolymers with P-gp inhibition for treatment of resistant solid tumors |
|
| Natálie Klusová, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Anti-tumor and immunomodulatory effect of polymeric conjugates based on HPMA carrying gemcitabine |
|
| Kevin Kotalík, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Water-soluble polymer conjugates with 5-aminolevulinic acid intended for photodynamic therapy |
|
| Alena Libánská, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Size-switchable polymer-based nanomedicines in the advanced therapy of rheumatoid arthritis |
|
| Ondřej Lidický, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Biocompatible polymers as tool for the antibody drug conjugate concept improvement |
|
| Dana Mareková, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic Biological evaluation of upconversion nanoparticles |
|
| Robert Pola, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Cytarabine nanotherapeutics with increased stability and different rate of hydrolytic release for highly effective antitumor therapy |
|
| Tomáš Přibyl, University of Chemistry and Technology, Prague, Czech Republic Formulation of molybdenum clusters for photodynamic cancer therapy |
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| Sára Pytlíková, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Hydrophilic polymer-pirarubicin conjugates for cancer treatment |
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| Anna Rumlerová, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic Polymer conjugates with antimicrobial peptides |
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| Johanne Seguine, Université Paris Cité, CNRS, INSERM, UTCBS lab, Paris, France Development and evaluation of optical imaging probes for tumor targeting |
|
| Daniil Starenko, Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic Polymeric conjugates with retroviral protease inhibitors as a potential way of overcoming chemoresistance in P-glycoprotein expressing tumors |
|
| Karolína Turnovcová, Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic Modeling of drug delivery to brain in vitro |
|
| Alžběta Turnovská, Institute of Macromolecular Chemistry, Czech Academy of Sciences, Prague, Czech Republic HPMA-based conjugates with porphyrins for photodynamic therapy and tumour imaging |
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